抄録
Offer Organization: Japan Society for the Promotion of Science, System Name: Grants-in-Aid for Scientific Research, Category: Grant-in-Aid for Young Scientists (B), Fund Type: competitive_research_funding, Overall Grant Amount: - (direct: 3200000, indirect: 960000)
Network of neurons generates variety of animal's activities such as moving, sensing and memorizing. While the properties of each neuron have been deeply examined, how assembly of neurons creates coherent and coordinated functions remains to be clarified. In this study, we dissected Drosophila larval motor circuits that generate spatiotemporal patterns of locomotion. We succeeded in identification of a group of interneurons(we named them "PMSI") which control the speed of the larval locomotion. By detailed analysis of PMSI using Ca imaging and optogenetics, we revealed some of the mechanisms how motor circuits regulate speed of locomotion.