抄録
Offer Organization: Japan Society for the Promotion of Science, System Name: Grants-in-Aid for Scientific Research, Category: Grant-in-Aid for Young Scientists (B), Fund Type: competitive_research_funding, Overall Grant Amount: - (direct: 3200000, indirect: 960000)
The utility of sperm cells in the epgenetic studies of autism was reviewed. It was concluded that sperm cells from the patients' fathers may be helpful for identifying the candidate genes for autism. It was also tried to establish the method of evaluating the genome-wide DNA methylation status by using microarrays, and investigate the DNA methylation status by using blood cells as a pilot study. As a result, the reproducibility of the method was not enough, and further improvement of the assessment procedure was recommended.